Commonly used modification equipment and characteristics of traditional Chinese medicine powder
The research on traditional Chinese medicine powder modification equipment started late, and the development is relatively lagging behind, mainly from the chemical industry, plastics, crushing, dispersion and other industries for reference. At present, the equipment used for traditional Chinese medicine powder modification mainly includes spray dryer, fluidized bed, ball mill, vibration mill, high-speed stirring mixer, airflow impact coating machine, continuous surface modification machine, Comil grinding and granulating machine, etc.
Among them, spray dryer, fluidized bed, ball mill and vibration mill are widely used in the field of traditional Chinese medicine powder modification. High-speed mixing mixer, air impact coating machine, continuous surface modification machine, Comil pulverizing and granulating machine, etc. have their own specific advantages in powder modification.
1. High-speed mixing mixer
When the high-speed mixing mixer is working, the material moves tangentially along the impeller with the help of the friction between the surface of the high-speed rotating blade and the material and the thrust of the side to the material. Due to the action of centrifugal force and gravity, the material is thrown to the inner wall of the mixing chamber. And it rises along the wall to a certain height and then falls back to the center of the impeller. This reciprocation causes the material to continuously move up and down in a spiral shape in the mixing chamber. The surface temperature of the material increases correspondingly, which promotes sufficient cross-mixing and adsorption between the drug powder particles and the modifier, so that the surface modifier coats the surface of the drug particles to achieve the purpose of powder surface modification.
2. Air impact cladding machine
There are many series of air impact cladding machines, and now the HYB system is taken as an example. The HYB system was developed by Tokyo University of Science and Nara Machinery in 1986. The main engine consists of a high-speed rotating rotor, stator and circulation loop.
3. Continuous Surface Modifier
When working, the material and modifier pass through the three mixing chambers in turn from the feeding port. The high-speed rotation of the rotor in the mixing chamber is forced to loosen the material and form a vortex two-phase flow. At the same time, the material passes through the impact and shear of the rotor and stator in the mixing chamber The energy required for surface modification is generated by the friction effect, so that the surface modifier can quickly interact with the surface of the drug powder particles to realize the powder coating modification effect.
4. Comil crushing and granulating machine
In recent years, some progress has been made in the application of Comil pulverizer and granulator to surface modification of chemical powder to improve the fluidity of chemical powder. Yu Yanhong et al. applied Comil pulverizer to improve the surface modification of traditional Chinese medicine extract powder The fluidity of traditional Chinese medicine extract powder has also achieved certain results.